Mouselook sucks! Even for mousers mouselook sucks. Mouselook is cheap because Mouselookers can turn faster than other players. Also, the ships don't fly properly with mouselook. I'd much rather have normal Descent mouse controls. Mouselook should not be an option. You can still attract the FPS crowd without mouselook. They can just use the normal mouse.
I have another question for High Octane Software:
Are the ship physics going to be like the Pyro-GX (D1 and D2) or will they be different? I hope you make the ship physics similar to the GX.
Oh, one more thing, I agree with that guy who posted earlier about the music. It's so easy to make spaceship games have techno music. Don't get me wrong; I like techno, but the D2 music rocked! It was so cool.

I also want to point out that this is not a "Descent remake," this is a new game.
Oh, I almost forgot...I like single-player! I find it funny that a lot of people don't like D3's single-player mode. But then I remember that most people who play Descent like shooting games, while I like action games. Action games don't work well in co-op mode. I'd like to see another mission with objectives and stuff, but I'll compromise, because it's not popular. The single-player should have simple objectives, or some other clear goals, without being an "endless key trail."
There should be robots for offline multiplayer. Don't make the robots like the ship robots in D3, because they either are noobs or they cheat! They don't have shields, either.
And try to optimize the weapons you design for multiplayer, but still be good weapons in single-player too. I hate it when a cool new weapon works well in SP but sucks in MP.